Category: Science

Shrinking Human Clickbait?

June 16, 2022 By arne hendriks Off

Hmmm, interesting. In the context of what seems to be the promotion of a new book on mammals, professor Steve Brusatte of the University of Edinburgh lists several all too well-known examples related to the phenomenon of shrinking as a survival mechanism when temperatures rise…

MCR3

November 7, 2021 By arne hendriks Off

According to research at the University of Cambridge the protein melanocortin receptor 3 appears to have an important role in linking signals of caloric sufficiency to the control of lineair growth of the human body. The research provides a mechanistic basis for the global secular…

Kohrisms

March 15, 2020 By arne hendriks Off

The Austrian economist and political scientist Leopold Kohr opposed the “cult of bigness” in social organization. He inspired the movement for a human scale and the Small Is Beautiful movement. His most influential work was The Breakdown of Nations. In 1983, he was awarded the Right Livelihood Award. In the…

Hallmarks of Malignant Growth: Limitless Replicative Potential

June 15, 2018 By arne hendriks Off

In trying to understand what makes continuous growth such a powerful idea (despite clear evidence that it often becomes harmful) The Incredible Shrinking Man turned to cancer research to learn where healthy growth turns malignant. Although cancer is a very complex phenomenon the seminal paper…

Neglecting Gravity

April 17, 2018 By arne hendriks Off

As Stephen Jay Gould writes in “Size and Shape” we are prisoners of the perceptions of our size, and rarely recognize how different the world must appear to the very small. Since our relative surface area is so small at our large size, we are…

Haplogroup Hot Switch

April 1, 2018 By arne hendriks Off

Haplogroup I-M170 is a common Y chromosome DNA haplogroup among unnecessary tall males mostly situated in North and South East Europe. The descendants sharing this specific group of identical genetic traits all come from a unique male ancestor that lived approximately 22.000 years ago during…

We are the Model Organism

April 3, 2015 By arne hendriks 0

The Incredible Shrinking Man is interested in the scientific culture of model organisms. A model organism is an animal species that is studied to understand particular biological phenomena, with the expectation that discoveries made in the organism model will provide insight into human biology. This research strategy is…

The Hayflick Limit

January 20, 2014 By arne hendriks 0

In 1961 microbiologist Leonard Hayflick demonstrated that a population of human fetal cells in a cell culture will divide approximately 50 times before they stop. With each cell division in our body the ends of our chromosomes, the telomeres, get slightly shorter. This process continues until they shorten to a critical…

7up 7down

November 5, 2013 By arne hendriks 1

Over the years science has put forth innumerable explanations as to why women outlive men. Of all people over 100 years or older 85% are women. Some think it is because men work harder than women. Others suggest it’s because women are more sociable and better at dealing…

Shrinking is Easy

September 5, 2013 By arne hendriks 1

There’s a basic asymmetry in macro-evolution. On the evolutionary scale shrinking is easy and growing large is difficult. This is probably due to the emergence, during a trend of increasing maximum body size, of a series of anatomical, physiological, environmental, genetic and other constraints that…

Zebrafish Portraits

June 7, 2013 By arne hendriks 0

Although our last common ancestor lived approximately 450 million years ago the genetic profile of the zebrafish, or Danio rerio, is surprisingly similar to human beings. In addition they are easy to breed, have transparent embryo development and are very cost effective. These, and many…

Growth Deceleration

November 11, 2012 By arne hendriks 0

Adult size isn’t just determined by how fast we grow. It depends also, and perhaps foremost, on how and when this growth stops. Somatic growth results from both cell proliferation (hyperplasia) and cell enlargement (hypertrophy). In mammals, somatic growth is rapid in embryonic and early postnatal…

180 Loci

September 26, 2012 By arne hendriks 1

Height is a classic polygenic trait which means it’s influenced by multiple genetic and environmental factors. Up to 90% of the variation in height is determined by inherited factors. Until now only a fraction of this 90% has been profiled succesfully. However, recent advances in…

Parental Height Minus 10

March 14, 2012 By arne hendriks 0

In an exiting paper by S. Matthew Liao,  Anders Sandberg, and Rebecca Roache, it is argued that human engineering may well be a reasonable tool to achieve a sustainable relationship between the planet and its human population. One of their more intriging suggestions is the possibility…

Hhp (Human Height Print)

December 5, 2011 By arne hendriks 2

Tall people need more resources than short people. That’s why it’s rather alarming that the human species continues to grow taller. In fact our increasing height puts more pressure on the ecosystem services than the total population growth. If people become 20% taller this creates over…

The Larons

November 9, 2011 By arne hendriks 2

People living in remote villages in Ecuador have a genetic mutation that may just hold the key to shrinking mankind. The villagers have a rare condition known as Laron syndrome. They are generally less than three and a half feet tall, they are proportional, and interestingly, they are…

(Mad) Scientist Fiction

October 24, 2011 By arne hendriks 1

Mankind seems so indoctrinated to think bigger that sometimes the mere suggestion that we should become smaller is thoughtlessly rejected as mad science. Ever since the 20th century our relationship with science, vacillating between science as the salvation of society or its doom, has been personified by…

Auxology Update

October 11, 2011 By arne hendriks 1

Auxology is the highly multi-disciplinary science that studies all aspects of human physical growth. It includes such diverse fields as economics, medicine, nutrition, and anthropology. Auxologists could, and perhaps should, play a key role in inspiring the cultural shift needed in order to accomplish a smaller…

Tall Risk

August 3, 2011 By arne hendriks 2

A study of 1,3 million women published in The Lancet Oncology finds that tall women are more likely to develop cancer. The researchers looked at the incidence of 17 cancer types, from breast cancer to leukemia, in a long-term health study across socio-economic levels. Cancer…

The ORC

June 26, 2011 By arne hendriks 0

Louise S. Bicknel of the Institute of Genetics and Molecular Medecine and Ernie M.H.F. Bongers of the Institute for Genetic and Metabolic Disease discovered which 5 genes are responsible for Meier-Gorlin Syndrome, a form of primordial dwarfism. Unlike with Dwarfism of Sindh MSG does create…